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HNF4a Pathway Mapping Identifies Wild-type IDH1 as a Targetable Metabolic Node in Gastric Cancer

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NIAID Data Ecosystem2026-04-30 收录
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https://www.ncbi.nlm.nih.gov/sra/SRP144507
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资源简介:
Comprehensive downstream mapping of HNF4a revealed its role in regulating GC metabolism via regulation of IDH1 Overall design: HNF4a ChIP-seq of GC cell lines, RNA-seq data of HNF4a perturbation and transcritome primary GC dataset were integrated to reveal HNF4a regulating biological processes and targets in GC, thus provide new therapeutic opportunity.
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2021-11-04
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