G10 Elicits IRF3 phosphorylation and Anti-Alphaviral Activity in Cells Lacking IPS1.
收藏Figshare2016-02-23 更新2026-04-29 收录
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https://figshare.com/articles/dataset/_G10_Elicits_IRF3_phosphorylation_and_Anti_Alphaviral_Activity_in_Cells_Lacking_IPS1_/1621533
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(A) Immunoblot of lysates from THF-ISRE-ΔIPS1 following 6h exposure to DMSO, UV-CMV, SeV or 100uM G10 as indicated showing phosphorylation status of IRF3 S386, total IRF3, IPS1, STING, and GAPDH. (B) Average media titers +SD of CHIKV, VEEV, and SINV at 24h (VEEV) or 48h (CHIKV, SINV) post infection obtained from THF-ISRE-ΔIPS1 cells treated with 1% DMSO, 100μM G10, or 1000U/mL IFNβ as indicated. Infections were performed in triplicate.
创建时间：
2016-02-23
