Crystal structure of mouse PRMT6 in complex with inhibitor LH1458
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Crystal structure of mouse PRMT6 in complex with inhibitor LH1458 Descriptor: 2-[(2~{R},3~{S},4~{R},5~{R})-5-(6-aminopurin-9-yl)-3,4-bis(oxidanyl)oxolan-2-yl]ethyl-[[4-azanyl-1-(methoxymethyl)-2-oxidanylidene-pyrimidin-5-yl]methyl]-[(3~{S})-3-azanyl-4-oxidanyl-4-oxidanylidene-butyl]azanium, Protein arginine N-methyltransferase 6 Authors: Cura, V, Marechal, N, Troffer-Charlier, N, Halby, L, Arimondo, P, Bonnefond, L, Cavarelli, J. Deposit date: 2016-09-12 Release date: 2017-09-20 Last modified: 2024-01-17 Method: X-RAY DIFFRACTION (1.802 Å) Cite: Hijacking DNA methyltransferase transition state analogues to produce chemical scaffolds for PRMT inhibitors. Philos. Trans. R. Soc. Lond., B, Biol. Sci., 373, 2018
创建时间：
2016-09-12
