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Estrogen Signaling in Arcuate Kiss1 Neurons Suppresses a Sex-Dependent Circuit That Promotes Dense Strong Bones in Female Mice

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NIAID Data Ecosystem2026-03-11 收录
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https://www.ncbi.nlm.nih.gov/geo/query/acc.cgi?acc=GSE122291
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Purpose: To characterize the estrogen receptor α (ESR1)-dependent transcriptome of neurons in the arcuate nucleus that regulate female bone density Method: Using RNA-Seq we compared gene expression profiles of microdissected arcuate nuclei from 3 control (Esr1fl/fl) and 3 conditional knockout (Esr1fl/fl;Nkx2-1-Cre) female mice.
创建时间:
2019-03-19
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