Benefits of dapagliflozin in the whole spectrum of heart failure in clinical practice: the RICA registry supplementary tables

Aims: To determine the projected benefits of dapagliflozin after an acute heart failure (HF) event in
Spain. Methods: A multicenter and prospective study that included subjects aged 50 years or older
consecutively admitted with HF to internal medicine departments in Spain. The projected clinical benefits
of dapagliflozin were calculated via pooled analysis of the DAPA-HF and DELIVER trials. Results: A total
of 5644 subjects were analyzed, of whom 79.2% were eligible for dapagliflozin, according to criteria
of the DAPA-HF and DELIVER trials. Full implementation of dapagliflozin would imply a 1-year absolute
risk reduction of 2.3% for death (number needed to treat = 43) and 5.7% (number needed to treat = 17)
for HF rehospitalization. Conclusion: Treatment with dapagliflozin could significantly reduce HF burden
in clinical practice.