Asymmetric Synthesis of trans-2,3-Disubstituted Indoline Derivatives
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https://figshare.com/articles/dataset/Asymmetric_Synthesis_of_i_trans_i_2_3_Disubstituted_Indoline_Derivatives/2565313
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资源简介：
A novel method for asymmetric synthesis of trans-2,3-disubstituted indolines has been developed. The strategy involves the (−)-sparteine-mediated electrophilic substitution of 2-benzyl N-pivaloylaniline with aromatic or α,β-unsaturated aldehydes and subsequent intramolecular nucleophilic substitution. The simple protocol for two-step process can produce highly enantioenriched indolines 3a–o up to 98:2 er.
创建时间：
2016-02-22
