Network of hotspot interactions cluster tau amyloid folds

Datafiles associated with <strong>Network of hotspot interactions cluster tau amyloid folds.</strong> The alascan files contain the averaged and raw outputs of the <em>in silico </em>alanine scan conducted on tau fibrils. The combo aggregation file contains ThT fluorescence data from the VQIVYK/VEVKSE alanine mutants and coaggregation experiments. The incorporation_vs_insilico file contains the results of the alanine scan top and bottom hits compared to the results of the incorporation experiment of alanine mutants on that position. Version 2: Files added providing data for how edge and center chains contribute to the total energetics, as well as a per-layer energy contribution to total deltaREU in the alanine scan of the PHF fibril.