首页/数据集/Druglikeness and side effects profile of bioactives targeting EGFR.

Druglikeness and side effects profile of bioactives targeting EGFR.

Figshare2022-04-14 更新2026-04-28 收录

数据链接：

https://figshare.com/articles/dataset/Druglikeness_and_side_effects_profile_of_bioactives_targeting_EGFR_/19600819 数据链接链接失效反馈

官方服务：

资源简介：

Druglikeness and side effects profile of bioactives targeting EGFR.

应用场景：

创建时间：

2022-04-14

EGFR靶向药物

抗癌药物开发

A new semisynthetic derivative of the natural alkaloid, theobromine, has been designed as a lead antiangiogenic compound targeting the EGFR protein. The designed compound is an (m-tolyl)acetamide theo

NIAID Data Ecosystem60

Crystal Structure of EGFR T790M mutant in complex with naquotinib

EGFR靶向药物

非小细胞肺癌治疗

Crystal Structure of EGFR T790M mutant in complex with naquotinib Descriptor: 6-ethyl-3-[[4-[4-(4-methylpiperazin-1-yl)piperidin-1-yl]phenyl]amino]-5-[(3R)-1-prop-2-enoylpyrrolidin-3-yl]oxy-pyrazin e-

Protein Data Bank Japan2024-10-30 更新30

Anti-Epidermal Growth Factor Receptor Gene Therapy for Glioblastoma

神经肿瘤基因治疗

EGFR靶向药物

Glioblastoma multiforme (GBM) is the most common and aggressive primary intracranial brain tumor in adults with a mean survival of 14 to 15 months. Aberrant activation of the epidermal growth factor r

Figshare2016-10-12 更新10

EGFR L858R/V948R in complex with osimertinib and allosteric inhibitor JBJ-09-063

EGFR靶向药物

变构抑制剂

EGFR L858R/V948R in complex with osimertinib and allosteric inhibitor JBJ-09-063 Descriptor: (2R)-2-(5-fluoro-2-hydroxyphenyl)-2-{6-[4-(1-methylpiperidin-4-yl)phenyl]-1-oxo-1,3-dihydro-2H-isoindol-2-y

Protein Data Bank Japan2024-11-20 更新40

File S1 - QSAR-Based Models for Designing Quinazoline/Imidazothiazoles/Pyrazolopyrimidines Based Inhibitors against Wild and Mutant EGFR

EGFR靶向药物

计算药物筛选

Table S1, Top 15 selected fragments favoured in wild type EGFR inhibitors. Table S2, Description of some selected chemical descriptors. Table S3, The pair-wise correlation values of 7 docking energy-b

Figshare2015-12-02 更新10

Druglikeness and side effects profile of bioactives targeting EGFR.

资源简介：

相关数据集