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Immunocompetent models of brain parenchymal and leptomeningeal metastasis. Immunocompetent models of brain parenchymal and leptomeningeal metastasis

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https://www.ncbi.nlm.nih.gov/bioproject/PRJNA913954
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Using iterative in vivo selection strategy, we generated a series of mouse metastatic lines with increased tropism for brain parenchyma or leptomeninges, to faithfully recapitulate the hallmarks of human disease. Overall design: RNA was collected from in vitro cultured parenchymal or leptomeningeal metastatic cells and along with parental cells subjected for transcriptomic analysis.
创建时间:
2022-12-19
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