Global analysis of the nuclear processing of unspliced U12-type introns by the exosome

ChEBI2014-05-26 更新2026-07-21 收录

RNA剪接调控

U12型内含子加工

数据链接：

https://www.ebi.ac.uk/biostudies/ArrayExpress/studies/E-GEOD-52539 数据链接链接失效反馈

官方服务：

资源简介：

Global analysis of the nuclear processing of unspliced U12-type introns by the exosome

创建时间：

2014-05-26

The impact of Prp18p on splicing fidelity and efficiency in budding yeast

剪接保真度

RNA剪接调控

Fidelity of 3´-splice site (3´SS) selection by the spliceosome is critical for proper gene expression but is a daunting task considering the low complexity of the 3´SS consensus YAG. Here we show that

Alliance of Genome Resources40

Glucose dissociates DDX21 dimers to regulate mRNA processing and promote epidermal differentiation (RNA-Seq II)

RNA剪接调控

表皮细胞分化

Glucose is an important cellular energy source, however, glucose's function as a second messenger remains relatively unexplored. Here, we find that glucose binds directly to DDX21 to regulate its func

NIAID Data Ecosystem30

Structure and Novel Functional Mechanism of Drosophila SNF in Sex-Lethal Splicing

RNA剪接调控

果蝇性别决定

Sans-fille (SNF) is the Drosophila homologue of mammalian general splicing factors U1A and U2B″, and it is essential in Drosophila sex determination. We found that, besides its ability to bind U1 snRN

NIAID Data Ecosystem30

ELAV/Hu RNA binding proteins determine multiple programs of neural alternative splicing. ELAV/Hu RNA binding proteins determine multiple programs of neural alternative splicing

RNA剪接调控

神经元mRNA处理

ELAV/Hu factors are conserved RNA binding proteins that play diverse roles in mRNA processing and regulation. The founding member, Drosophila Elav, was recognized as a vital neural factor 35 years ago

NIAID Data Ecosystem40

The zinc finger domains in U2AF26 and U2AF35 have diverse functionalities including a role in controlling translation

RNA剪接调控

翻译控制

Recent work has associated point mutations in both zinc fingers (ZnF) of the spliceosome component U2AF35 with malignant transformation. However, surprisingly little is known about the functionality o

NIAID Data Ecosystem30

Global analysis of the nuclear processing of unspliced U12-type introns by the exosome

资源简介：

相关数据集