Public search interest in polydeoxyribonucleotide (PDRN) and polynucleotides: Google Trends dataset, 2019–2026

This dataset contains monthly Google Trends relative search volume (RSV) data on polydeoxyribonucleotide (PDRN) and polynucleotide-related search terms from January 2019 to October 2026, together with annual PubMed record counts for the same topic. Two comparison sets were extracted. Set A covers PDRN, polynucleotides, salmon sperm facial, Rejuran and Profhilo. Set B covers PDRN serum, PDRN cream, polynucleotide injection, salmon sperm facial and Profhilo. Regions are Worldwide, South Korea, United Kingdom and United States, with Türkiye included for Set A only. A third set (South Korea only) uses Korean-language terms. Profhilo was kept in every set as a common reference term. All data were extracted on 1 November 2026 as search terms (web search, all categories). RSV values are normalised within each set and region and should not be compared across sets or regions. Values exported as "<1" are kept verbatim and set to 0.5 for calculations. The README sheet describes each variable and the PubMed query used. The dataset supports a manuscript on public interest in PDRN/polynucleotides relative to the available clinical evidence.