Crystal structure of CHK1-10pt-mutant complex with compound 3
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Crystal structure of CHK1-10pt-mutant complex with compound 3 Descriptor: 2-methyl-2-(3-methyl-4-{[4-(methylamino)-5-(trifluoromethyl)pyrimidin-2-yl]amino}-1H-pyrazol-1-yl)propanenitrile, CHLORIDE ION, Serine/threonine-protein kinase Chk1 Authors: Dokurno, P, Surgenor, A.E, Williamson, D.S. Deposit date: 2021-01-14 Release date: 2021-07-07 Last modified: 2024-01-31 Method: X-RAY DIFFRACTION (2 Å) Cite: Design and Synthesis of Pyrrolo[2,3- d ]pyrimidine-Derived Leucine-Rich Repeat Kinase 2 (LRRK2) Inhibitors Using a Checkpoint Kinase 1 (CHK1)-Derived Crystallographic Surrogate. J.Med.Chem., 64, 2021
创建时间：
2021-01-14
