Crystal structure of human adenovirus 8 protease with an irreversible vinyl sulfone inhibitor
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Crystal structure of human adenovirus 8 protease with an irreversible vinyl sulfone inhibitor Descriptor: N-[(2S)-2-(3,5-dichlorophenyl)-2-(ethylamino)acetyl]-3-methyl-L-valyl-N-[3-(methylsulfonyl)propyl]glycinamide, PVI, Protease Authors: Grosche, P, Sirockin, F, Mac Sweeney, A, Ramage, P, Erbel, P, Melkko, S, Bernardi, A, Hughes, N, Ellis, D, Combrink, K, Jarousse, N, Altmann, E. Deposit date: 2014-11-13 Release date: 2015-01-14 Last modified: 2024-11-13 Method: X-RAY DIFFRACTION (2.15 Å) Cite: Structure-based design and optimization of potent inhibitors of the adenoviral protease. Bioorg.Med.Chem.Lett., 25, 2015
创建时间：
2014-11-13
