Single-cell RNA sequencing of healthy and inflamed murine neutrophils

Dataset containing single-cell RNA sequencing data of >17,000 healthy and perturbed murine neutrophils across biological tissues. This study contains expression data from healthy tissues (bone marrow, spleen, peripheral blood) as well as models of experimental (K/BxN serum transfer arthritis: peripheral blood and joint, IL-1ß peritonitis and IL-1ß pneumonitis). Single cell RNA-sequencing was performed on the 10X platform Overall design: CD11b+ Ly6G+ PI-negative live neutrophils were sorted from healthy tissues (bone marrow, spleen, peripheral blood) and models of experimental inflammation (K/BxN serum transfer arthritis: peripheral blood and joint, IL-1ß peritonitis and IL-1ß pneumonitis) and single cell RNA-sequencing was performed on the 10X platform.