f354bc6a-9b0f-46d2-ab78-991d411b8c49 - samples
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https://www.omicsdi.org/dataset/ega/EGAD00001005456
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There are two samples, 42 (control) and 49
To test the role of activated CRLF2/IL7RA in leukemia initiation we expressed CRLF2 together with IL7RA in human CB hematopoietic progenitors. Human CRLF2 and wild type and/or activated mutant form of human IL7RA (IL7RAwt/ins) were cloned into a lentiviral vector with a bi-cistronic cassette under the expression control of an Eμ-B29 promoter/enhancer to augment expression in B-cell precursors. Backbone vector expressing GFP (BB).
Whole genome sequencing
Leukemic (49) and BB transduced (42) corresponding CB cells were collected from transplanted mice. Sequencing libraries were prepared from these samplesEGA dataset EGAD00001005456
创建时间:
2021-07-28



