Pogz deficiency leads to abnormal behavior, transcription dysregulation and impaired cerebellar physiology

As part of characterizing the novel pogz deficiency mouse model, we performed RNA-Seq from cerebellum and hippocampus of adult mice to discover Pogz targets and changes in gene expression that might explain the phenotypes we see in those mice Overall design: Cerebellar and hippocampal mRNA profiles of control (WT), pogz+/- and pogz-/- mice, both males and females, in triplicates, using Illumina NextSeq 500