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PDE4 Inhibition of rolipram and sulfonamides 5 and 6a-k.

NIAID Data Ecosystem2026-03-09 收录

PDE4抑制剂

药物活性评估

数据链接：

https://figshare.com/articles/dataset/PDE4_Inhibition_of_rolipram_and_sulfonamides_5_and_6a-k_/3982959 数据链接链接失效反馈

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资源简介：

PDE4 Inhibition of rolipram and sulfonamides 5 and 6a-k.

应用场景：

创建时间：

2016-10-04

配位聚合物

药物活性评估

Two new mixed-ligand coordination polymers with the chemical formulae of {[Zn3(nbta)2(bpfp)2(H2O)2](H2O)2}n (1, H3nbta = 5-nitro-1,2,3-benzenetricarboxylic acid, bpfp = bis(4-pyridylformyl)piperazine)

NIAID Data Ecosystem160

Discovery of Potent and Selective Periphery-Restricted Quinazoline Inhibitors of the Cyclic Nucleotide Phosphodiesterase PDE1

PDE4抑制剂

心血管疾病

We disclose the discovery and X-ray cocrystal data of potent, selective quinazoline inhibitors of PDE1. Inhibitor (S)-3 readily attains free plasma concentrations above PDE1 IC50 values and has restri

NIAID Data Ecosystem40

STACs suppress stimuli-induced NF-κB transcriptional activation and cytokine secretion.

NF-κB抑制剂

药物活性评估

Table shows the IC50 values of the STACs in NF-κB luciferase reporter assay and LPS-induced TNFα secretion assay.

NIAID Data Ecosystem40

peptide raw data

药物活性评估

抗菌药物联合效应

mic for the peptide and antibiotics hemolysis study combinationshplc and mass spectrum

Figshare2023-08-05 更新80

Summary of IC50 and EC50 values for different ligands in multiple functional assays.