Transcription profiling of mouse microvascular transcriptomes

Little is known about the pan-microvascular transcriptome, particularly considering gene transcripts and their encoded proteins that can be considered as vascular-selective in their expression. Using a combination of publicly available and our own transcript profiles, we identified a core set of gene transcripts, which are specifically and broadly expressed in the microvasculature. Experiment Overall Design: There are three different samples, each have three biological repeats. Comparisons were carried out between the samples.目前学界对泛微血管转录组（pan-microvascular transcriptome）的认知仍较为有限，尤其针对表达具有血管选择性的基因转录本及其编码蛋白而言。本研究整合公共可用的转录组谱与本团队自主获得的转录组数据，鉴定得到一组核心基因转录本，该类转录本可在微血管组织中特异性且广泛表达。实验整体设计：本研究共设置3组独立样本，每组均包含3次生物学重复；各组样本间开展了对比分析。