Associations between PIK3CA-KCNMB3 variants and glucose-related traits in the GOLDN and BPRHS participants1.

1Values are mean ± SEM. P-values were adjusted for age, sex, waist circumference, alcohol drinking, smoking status, physical activity, type 2 diabetes, study center and family relationships in GOLDN; P-values were adjusted for age, sex, waist circumference, alcohol drinking, smoking status, physical activity, type 2 diabetes and population admixture in BPRHS. Meta-analysis was used to combine Z statistics across GOLDN and the BPRHS, weighted by the sample size; I2 was used to assess statistical heterogeneity: I2 values of 25%, 50% and 75% correspond to cut-off points for low, moderate and high degrees of heterogeneity.