Synthesis of Indolizines via Palladium Catalyzed Annulation of Propargyl Carbonates and 2‑(Pyridin-2-yl)acetonitrile Derivatives
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A Pd-catalyzed regioselective annulation reaction of propargyl carbonates and 2-(pyridine-2-yl) acetonitrile derivatives has been accomplished, which provides a straightforward and efficient access to polysubstituted indolizines. The choice of the phosphine ligand is crucial to the high regio-selectivity of the reaction.
创建时间：
2017-10-11
