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GrM - Human and mouse granzyme M display divergent and species-specific substrate specificities

NIAID Data Ecosystem2026-03-07 收录

免疫蛋白酶体

物种特异性酶功能

数据链接：

https://www.omicsdi.org/dataset/pride/PRD000347 数据链接链接失效反馈

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资源简介：

Complementary positional proteomics of human and mouse granzyme M treated K-562 lysates

应用场景：

创建时间：

2012-05-23

免疫蛋白酶体

癌细胞系

The degradation of intracellular proteins is a dynamic and tightly regulated process. Most of such substrates is hydrolyzed by proteasomes. Different forms of proteasomes are known. The role of immuno

NIAID Data Ecosystem50

Crystal Structure of D86N-GzmM Complexed with Its Optimal Synthesized Substrate

蛋白质晶体学

免疫蛋白酶体

Crystal Structure of D86N-GzmM Complexed with Its Optimal Synthesized Substrate Descriptor: Granzyme M, SSGKVPLS, SULFATE ION Authors: Wu, L.F, Wang, L, Hua, G.Q, Liu, K, Zhai, Y.J, Sun, F, Fan, Z.S.

Protein Data Bank Japan2024-10-30 更新40

AAA ATPase domain of the proteasome- activating nucleotidase

AAAATPase结构域

免疫蛋白酶体

AAA ATPase domain of the proteasome- activating nucleotidase

NIAID Data Ecosystem20

A cell-based platform for the investigation of immunoproteasome subunit β5i expression and biology of β5i-containing proteasomes

免疫蛋白酶体

CRISPR-Cas9

NIAID Data Ecosystem40

Engineering A Potent Cancer Vaccine Using Immunoproteasome-Expressing Mesenchymal Stromal Cells. Engineering A Potent Cancer Vaccine Using Immunoproteasome-Expressing Mesenchymal Stromal Cells

癌症疫苗

免疫蛋白酶体

Raw RNA-seq counts from reads aligned to the mouse genome (mm10 assembly) were generated with Htseq-count (PMID: 25260700). Differentially expressed genes between IPr and Ctl MSCs were calculated by D

NIAID Data Ecosystem30

GrM - Human and mouse granzyme M display divergent and species-specific substrate specificities

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