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Hypoxia-induced Arterial Differentiation Requires Adrenomedullin and Notch Signaling

ChEBI2013-02-08 更新2026-07-21 收录

缺氧适应机制

Notch信号通路

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https://www.ebi.ac.uk/biostudies/ArrayExpress/studies/E-GEOD-35894 数据链接链接失效反馈

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Hypoxia-induced Arterial Differentiation Requires Adrenomedullin and Notch Signaling

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创建时间：

2013-02-08

缺氧适应机制

果蝇转录组学

Hypoxia plays a key pathogenic role in the outcome of many pathologic conditions. To elucidate how organisms successfully adapt to hypoxia, a population of Drosophila melanogaster was generated, throu

NIAID Data Ecosystem90

ADAM10 Negatively Regulates Neuronal Differentiation during Spinal Cord Development

脊髓发育调控

Notch信号通路

Members of the ADAM (a disintegrin and metalloprotease) family are involved in embryogenesis and tissue formation via their proteolytic function, cell-cell and cell-matrix interactions. ADAM10 is expr

NIAID Data Ecosystem50

DELTA1/NOTCH2-mediated signaling regulates muscle stem cell self-renewal

干细胞研究

Notch信号通路

How satellite cells and their progenitors balance differentiation and self-renewal to achieve sustainable tissue regeneration is not well understood. A major roadblock to understanding satellite cell

NIAID Data Ecosystem20

YTHDF1 links hypoxia adaptation and non-small cell lung cancer progression

非小细胞肺癌蛋白质组学

缺氧适应机制

10plex TMT labelling quantification expriments were performed to access the knockdown effect of YTHDF1 in cells.3 shGFPs control samples, 3 YTHDF1 shRNA-2 knockdown samples , 3 YTHDF1 shRNA-3 knockdow

NIAID Data Ecosystem90

Oncogenic Notch promotes long-range regulatory interactions within hyperconnected 3D cliques [Rec1_ChIP-seq]

癌症三维基因组学

Notch信号通路

Purpose: To investigate the impact of oncogenic Notch on the 3D genome organization of cancer cells. Methods: We generated cohesin HiChIP and 1D epigenomic data sets in two different Notch-dependent c

NIAID Data Ecosystem50

Hypoxia-induced Arterial Differentiation Requires Adrenomedullin and Notch Signaling

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