Global gene expression of mesenchymal like lung cancer cell (TD) induced by TGFb with control (A549)

Analysis of TGF-ß induced mesenchymal type of lung cancer compared with control A549 lung cancer cell at gene expression level. In order to investigate the characteristics of mesenchymal like lung cancer cell, we established mesenchymal type of lung cancer cell (TD) with chronic exposure with TGF-ß. After we established TD cell line, RNA-seq was performed with total RNA extracted from TD and parental A549 cells. Overall design: Total RNA obtained from mesenchymal like lung cancer cells (TD) and control A549 cells