k-mer analysis in Ivorian A. coluzzii.

A) Alignment coordinates of k-mers that are significantly associated with pirimiphos-methyl resistance in Ivorian A. coluzzii samples from the Anopheles gambiae 1000 Genomes Phase 2. For each k-mer, we report the alignment sequence and coordinates, and whether it overlaps the Ace1 gene or the Ace1 duplication. This table includes both primary and secondary alignments as reported by bwa mem, as well as non-aligned k-mers (chromosome “NA”). B) Correlation of alignment frequencies and Ace1 copy number in each sample, for each of the 409 k-mers that mapped to chromosomal arms 2R, 2L, 3R, 3L or X. We report Pearson’s correlation coefficients (r) and p-values. C) Sequences of the 446 assembled k-mers that are significantly associated with pirimiphos-methyl resistance. D) Frequencies of the 9,603 k-mers (before assembly) in each of the Côte d’Ivoire A. coluzzii samples (Anopheles gambiae 1000 Genomes Phase 2, n = 71). (XLSX)