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Blood transcriptome sequencing of cynomolgus monkeys

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NIAID Data Ecosystem2026-05-02 收录
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https://www.ncbi.nlm.nih.gov/sra/SRP439997
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We generated PSEN1 mutant macaques by genomic deletion of exon 9 using two guide RNAs targeting the upstream and downstream intron sequences of PSEN1 exon 9, respectively. Here, blood transcriptome sequencing was performed on these 5-month-old control and mutant monkeys to assess the potential impact of familial Alzheimer's disease-associated PSEN1 mutations on juvenile monkeys.
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2024-06-01
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