Recent experimental studies have defined intracranial aneurysms as a macrophage-mediated chronic inflammatory disease affecting intracranial arteries. We used single cell RNA sequencing (scRNA-seq) to

NIAID Data Ecosystem40

shRNAi profiling of human MDA-MB-231 cells expressing anti-p53 (shp53) short-hairpin RNAs treated with TFGbeta or control

癌症转移机制

转录组功能分析

TGFβ ligands act as tumor suppressors in early stage tumors but are paradoxically diverted into potent prometastatic factors in advanced cancers. The molecular nature of this switch remains enigmatic.

NIAID Data Ecosystem30

Additional file 2 of Understanding the early cold response mechanism in IR64 indica rice variety through comparative transcriptome analysis

水稻胁迫响应

转录组功能分析

Additional file 2. Sheet 1 contains a table for GO enrichment, genes for each functional category for upregulated DEGs. Sheet 2 contains a table showing KEGG Brite analysis for cold induced DEGs.

Figshare2020-06-25 更新50

SMCHD1 activates the expression of genes required for the expansion of human myoblasts (RNA-seq). SMCHD1 activates the expression of genes required for the expansion of human myoblasts (RNA-seq)

肌肉疾病分子机制

转录组功能分析

In human muscle, SMCHD1 mutations are associated with the onset of FSHD2, but the mechanism driving the disease onset remains unclear. A commonly accepted explanation is the loss of SMCHD1 binding to

NIAID Data Ecosystem40

Expression data from wild type and Gata6-deficient tissue resident peritoneal macrophages

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