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Analysis of transcriptomes of naive CD4+ T cells, polarized under Th17 cell skewing conditions for 24h in presence or abscence of CK2 Inhibitor. Mus musculus

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NIAID Data Ecosystem2026-03-09 收录
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The goal of this study was to elucidate the transcriptional changes evoked by CK2 inhibition in developing Th17 cells Overall design: Messenger RNA profiles of naive CD4+ T cells, FACS-purifed from spleens of C57BL6 mice and stimulated with plate-bound anti-CD3 and anti-CD28 for 24h under Th17 polarizing conditions in presence or abscence of CK2 inhbititors DMAT (1.5µM) or CX4945 (1µM) were generated by sequencing using Illumina MiSeq

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2016-08-11
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