five

2.8A structure of etoposide with S.aureus DNA gyrase and DNA

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Protein Data Bank Japan2024-11-13 更新2026-03-21 收录
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2.8A structure of etoposide with S.aureus DNA gyrase and DNA Descriptor: (5S,5aR,8aR,9R)-9-(4-hydroxy-3,5-dimethoxyphenyl)-8-oxo-5,5a,6,8,8a,9-hexahydrofuro[3',4':6,7]naphtho[2,3-d][1,3]dioxol -5-yl 4,6-O-[(1R)-ethylidene]-beta-D-glucopyranoside, DNA (5'-D(P*GP*AP*GP*CP*GP*TP*AP**GP*GP*CP*CP*GP*TP*AP*CP*GP*CP*TP*C)-3'), DNA (5'-D(P*GP*AP*GP*CP*GP*TP*AP*C*GP*GP*CP*CP*GP*TP*AP*CP*GP*CP*TP*C)-3'), ... Authors: Bax, B.D, Srikannathasan, V, Chan, P.F. Deposit date: 2015-07-04 Release date: 2015-12-16 Last modified: 2024-11-13 Method: X-RAY DIFFRACTION (2.79 Å) Cite: Structural basis of DNA gyrase inhibition by antibacterial QPT-1, anticancer drug etoposide and moxifloxacin. Nat Commun, 6, 2015
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2015-07-04
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