Neurochemical and cognitive changes precede structural abnormalities in the TgF344-AD rat model

Raw data for manuscript accepted in Brain Communications, awaiting official publication. All datasets contain subject information and modality-specific data. Data was acquired longitudinally at four timepoints from hemizygous TgF344-AD rats (transgenic AD model bred on a Fischer 344 background) and wildtype littermates. 

1) Barnes Maze probe data. Probe data acquired 48 hours after last training trial. 

2) Magnetic Resonance Spectroscopy data: absolute concentrations are provided, as well as relative to total creatine. 

3) Magnetic Resonance Imaging data: absolute brain volumes generated from absolute jacobians. "Brain-size-corrected" volumes are referred to as "relative" volumes and are generated from relative jacobians.