Supplementary Figure 4. gH mAbs are specific for HCMV neutralization. Neutralization of HSV-1 US-11 GFP (MOI 0.01) using anti-gH mAbs (50-0.016 ug/mL) and assessed usingGFP as a readout for infection
A summary of geometric mean titers of PRNT50 GMT for comparison between the two ZIKV strains, MR-766 and FSS 13025 for both vaccine and virus control groups. Neutralizing activity elicited by the VLP
1days post onset of symptoms. 2Last positive titer in 90% Focus-reduction micro-neutralization (FRμNT) assay. 3Calculated actual 90% neutralization titers based on a nonlinear regression of the FRμNT
aGuinea pigs were treated i.p. with 5 mg of the MAb as shown in the table on day 1 after infection with 1000 LD50 of the GA-ZEBOV. Survival of the guinea pigs was followed. The Student's T-test compar