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Crystal structure of the L317I mutant of the C-src tyrosine kinase domain complexed with dasatinib

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Protein Data Bank Japan2023-09-13 更新2026-03-21 收录
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Crystal structure of the L317I mutant of the C-src tyrosine kinase domain complexed with dasatinib Descriptor: N-(2-CHLORO-6-METHYLPHENYL)-2-({6-[4-(2-HYDROXYETHYL)PIPERAZIN-1-YL]-2-METHYLPYRIMIDIN-4-YL}AMINO)-1,3-THIAZOLE-5-CARBOXAMIDE, Proto-oncogene tyrosine-protein kinase Src Authors: Boubeva, R, Pernot, L, Perozzo, R, Scapozza, L. Deposit date: 2011-02-02 Release date: 2012-02-08 Last modified: 2023-09-13 Method: X-RAY DIFFRACTION (2.75 Å) Cite: A single amino-acid dictates the dynamics of the switch between active and inactive C-src conformation To be Published
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2011-02-02
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