We showed previously that POLG mutations cause major changes in mitochondrial function, including loss of mitochondrial respiratory chain (MRC) complex I, mitochondrial DNA (mtDNA) depletion and an ab
Additional file 9: Table S5. Proteomic analysis of ONL and PS from $$rod^{\varDelta\ Vhl}$$ r o d Δ V h l and ctrl mice; includes UniProt IDs, number of unique peptides, ensembl IDs, gene symbols and
Cell culture conditions highly influence cell metabolism in vitro. This is relevant for preclinical assays, for which fibroblasts are an interesting cell model, with applications in regenerative medic
Mitochondria are the metabolic hubs that process a number of reactions including tricarboxylic acid cycle, β-oxidation of fatty acids and part of the urea cycle and pyrimidine nucleotide biosynthesis.
