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Crystal structure of PDE2 catalytic domain in complex with BAY60-7550

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Protein Data Bank Japan2023-09-20 更新2026-03-21 收录
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Crystal structure of PDE2 catalytic domain in complex with BAY60-7550 Descriptor: 2-(3,4-dimethoxybenzyl)-7-[(2R,3R)-2-hydroxy-6-phenylhexan-3-yl]-5-methylimidazo[5,1-f][1,2,4]triazin-4(3H)-one, MAGNESIUM ION, ZINC ION, ... Authors: Zhu, J, Huang, Q. Deposit date: 2012-11-02 Release date: 2013-08-28 Last modified: 2023-09-20 Method: X-RAY DIFFRACTION (1.9 Å) Cite: X-ray Crystal Structure of Phosphodiesterase 2 in Complex with a Highly Selective, Nanomolar Inhibitor Reveals a Binding-Induced Pocket Important for Selectivity. J.Am.Chem.Soc., 135, 2013
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2012-11-02
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