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Bioactive Limonoids and Triterpenoids from the Fruits of <i>Melia azedarach</i>

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NIAID Data Ecosystem2026-03-12 收录
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Nine new limonoids, meliazedarines A–I (1–9), seven known analogues (10–16), and five known triterpenoids (17–21) were isolated from the fruits of Melia azedarach. Their structures were determined by analysis of 1D and 2D NMR, HRESIMS, X-ray diffraction, and electronic circular dichroism (ECD) data. Compound 7 showed significant cytotoxicity against the HCT116 cell line with IC50 values of 0.3 ± 0.1 μM.

创建时间:
2020-11-30
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