Adenosine 3',5'-bisphosphate (PAP) + H2O => AMP + orthophosphate

PAP is generated as a byproduct of sulfonation reactions in vivo; its hydrolysis to AMP and orthophosphate returns its constituents to the pool of molecules available for cytosolic nucleotide metabolism. Bisphosphate 3'-nucleotidase 1catalyzes this reaction efficiently in vitro; whether other nucleotidases also play a role in PAP breakdown in vivo is unknown.

PAP 作为体内磺化反应的副产品生成；其水解生成 AMP 和正磷酸，使组成成分回归至胞质核苷酸代谢的分子库中。Bisphosphate 3'-核苷酸酶 1 在体外有效催化此反应；然而，其他核苷酸酶是否在体内 PAP 分解中亦发挥作用，尚属未知。