Clinical and phenotypic characteristics of the Saguenay–Lac-St-Jean association study sample subjects.

*FEV1 = Geometric mean of the force expiratory volume in one second evaluated for 208 probands and for 683 family members.
†PC20 = Concentration of methacholine inducing a 20% fall in FEV1. Geometric mean and SD were obtained from the log transformed PC20 values. Evaluated for 186 probands and for 614 family members.
‡IgE = Immunoglobulin E serum concentration. Geometric mean and SD were obtained from the log transformed IgE values. Evaluated for 211 probands and 704 family members.
§Present asthma or past documented clinical history of asthma. The reported mean age of onset is 7 years among the asthmatic probands and 22 years among the asthmatic family members.
∏Defined as at least one positive response on skin prick testing (wheal diameter >3 mm at 10 minutes).