Calculating the surface-area ratio of UBM to ileum after AC in a control bladder.

AC, augmentation cystoplasty.AC was initially performed with ileum (25 cm2) and percentage increases in capacity were recorded at 2 mmHg. Subsequently, AC was performed on the control with UBM scaffolds ranging from 20 cm2 to 80 cm2 and percentage increases were compared at 2 mmHg to ileal values. AC with an 8×6.5 cm (50 cm2) UBM scaffold resulted in a 40.7% increase in bladder capacity compared to an increase of 40.0% with a 5×5 cm (25 cm2) of detubularised ileum at 2 mmHg. Hence, 50 cm2 UBM scaffolds were applied to ovine bladders for comparative purposes with ileum after AC.