Chromosomal rearrangements juxtapose the TERT coding sequence to strong enhancer elements
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https://www.ncbi.nlm.nih.gov/sra/SRP253263
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Chromatin immunoprecipitation (ChIP) sequencing with an anti-acetyl-H3K27 antibody showed an enhancer region rearranged to the TERT gene, and ChIP sequencing with an anti-BRD4 antibody showed BRD4 protein binding to the enhancer in TERT-rarranged neuroblasstoma PDX CCI-NB07-RMT cells Overall design: Examination of H3K27ac signal and BRD4 binding in TERT-rearranged neuroblastoma PDX cells
创建时间:
2021-03-01



