The structure of the polo-box domain (PBD) of polo-like kinase 1 (Plk1) in complex with JES107
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The structure of the polo-box domain (PBD) of polo-like kinase 1 (Plk1) in complex with JES107 Descriptor: 2-[[3-[[5-(3-iodanylphenyl)carbonylthiophen-2-yl]carbonylamino]phenyl]methyl]propanedioic acid, Serine/threonine-protein kinase PLK1 Authors: Kunciw, D.L, Rossmann, M, Stokes, J.E, De Fusco, C, Spring, D.R, Hyvonen, M. Deposit date: 2017-03-10 Release date: 2018-02-21 Last modified: 2026-05-13 Method: X-RAY DIFFRACTION (2.68 Å) Cite: A cryptic hydrophobic pocket in the polo-box domain of the polo-like kinase PLK1 regulates substrate recognition and mitotic chromosome segregation. Sci Rep, 9, 2019
创建时间:
2017-03-10



