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ROR(gamma)t ligand binding domain in complex with cholesterol and allosteric ligand FM26

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Protein Data Bank Japan2024-01-24 更新2026-03-21 收录
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ROR(gamma)t ligand binding domain in complex with cholesterol and allosteric ligand FM26 Descriptor: 4-[(~{E})-[3-[2-chloranyl-6-(trifluoromethyl)phenyl]-5-(1~{H}-pyrrol-3-yl)-1,2-oxazol-4-yl]methylideneamino]benzoic acid, CHOLESTEROL, GLYCEROL, ... Authors: de Vries, R.M.J.M, Meijer, F.A, Brunsveld, L. Deposit date: 2019-10-14 Release date: 2020-11-25 Last modified: 2024-01-24 Method: X-RAY DIFFRACTION (1.93 Å) Cite: Cooperativity between the orthosteric and allosteric ligand binding sites of ROR gamma t. Proc.Natl.Acad.Sci.USA, 118, 2021
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2019-10-14
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