Single-cell transcriptome profiles of wild-type and IRF8KO microglia [scRNA-seq]
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https://www.ncbi.nlm.nih.gov/geo/query/acc.cgi?acc=GSE231405
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资源简介：
The role of the lineage-determining transcription factor IRF8 in microglia remains unelucidated. We analyzed the transcriptome diversity of wild-type and IRF8KO microglia. Deep-sequencing and subsequent differential analysis revealed the significance of the IRF8-dependent transcription on microglial heterogeneity and self-renewing. This study provides a novel insight into understanding IRF8-mediated transcriptional programs in microglia. Transcriptome profiles of adult WT and IRF8KO microglia were analyzed at a single-cell level using 10xGenomics.
创建时间：
2023-08-31
