Crystal Structure of Human Coagulation Factor XA Complexed with FXV673
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Crystal Structure of Human Coagulation Factor XA Complexed with FXV673 Descriptor: CALCIUM ION, COAGULATION FACTOR XA, METHYL-3-(4'-N-OXOPYRIDYLPHENOYL)-3-METHYL-2-(M-AMIDINOBENZYL)-PROPIONATE Authors: Maignan, S, Guilloteau, J.P. Deposit date: 2002-01-14 Release date: 2002-06-19 Last modified: 2024-11-20 Method: X-RAY DIFFRACTION (2.1 Å) Cite: Optimization of the beta-aminoester class of factor Xa inhibitors. Part 2: Identification of FXV673 as a potent and selective inhibitor with excellent In vivo anticoagulant activity. Bioorg.Med.Chem.Lett., 12, 2002
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2002-01-14
