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Crystal structure of human tryptophan hydroxylase 1 in complex with inhibitor KM-05-193

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Protein Data Bank Japan2024-01-31 更新2026-04-19 收录
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https://pdbj.org/mine/summary/7zii
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Crystal structure of human tryptophan hydroxylase 1 in complex with inhibitor KM-05-193 Descriptor: 8-(5~{H}-[1,3]dioxolo[4,5-f]benzimidazol-6-ylmethyl)-7-(phenylmethyl)-3-propyl-purine-2,6-dione, FE (III) ION, GLYCEROL, ... Authors: Schuetz, A, Mallow, K, Nazare, M, Specker, E, Heinemann, U. Deposit date: 2022-04-08 Release date: 2022-09-07 Last modified: 2024-01-31 Method: X-RAY DIFFRACTION (1.62800050605 Å) Cite: Structure-Based Design of Xanthine-Benzimidazole Derivatives as Novel and Potent Tryptophan Hydroxylase Inhibitors. J.Med.Chem., 65, 2022
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2022-04-08
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