Crystal structure of haspin (GSG2) in complex with bisubstrate inhibitor ARC-3353.
收藏Protein Data Bank Japan2025-07-09 更新2026-03-21 收录
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Crystal structure of haspin (GSG2) in complex with bisubstrate inhibitor ARC-3353. Descriptor: (2R,3S,4R,5R,6R)-6-((1R,2R,3S,4R,6S)-4,6-DIAMINO-2,3-DIHYDROXYCYCLOHEXYLOXY)-5-AMINO-2-(AMINOMETHYL)-TETRAHYDRO-2H-PYRAN-3,4-DIOL, (3R)-4-amino-3-{[6-({[(2S,3S,4R,5R)-5-(6-amino-9H-purin-9-yl)-3,4-dihydroxytetrahydrofuran-2-yl]carbonyl}amino)hexanoyl]amino}-4-oxobutanoic acid (non-preferred name), (4R)-2-METHYLPENTANE-2,4-DIOL, ... Authors: Chaikuad, A, Heroven, C, Lavogina, D, Kestav, K, Uri, A, von Delft, F, Arrowsmith, C.H, Edwards, A.M, Bountra, C, Knapp, S, Structural Genomics Consortium (SGC) Deposit date: 2016-01-26 Release date: 2016-05-11 Last modified: 2025-07-09 Method: X-RAY DIFFRACTION (1.7 Å) Cite: Co-crystal structures of the protein kinase haspin with bisubstrate inhibitors. Acta Crystallogr.,Sect.F, 72, 2016
创建时间：
2016-01-26
