five

Crystal structure of SARS CoV-2 3CL protease in complex with GSK4365096A

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Protein Data Bank Japan2024-11-20 更新2026-04-11 收录
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Crystal structure of SARS CoV-2 3CL protease in complex with GSK4365096A Descriptor: 3C-like proteinase nsp5, N-[(benzyloxy)carbonyl]-4-fluoro-L-phenylalanyl-N-{(2R)-1-[(2S)-oxolan-2-yl]-3-[(3S)-2-oxooxolan-3-yl]propan-2-yl}-L-leucinamide Authors: Concha, N.O, Williams, S.P. Deposit date: 2023-10-10 Release date: 2024-02-14 Last modified: 2024-11-20 Method: X-RAY DIFFRACTION (2.02 Å) Cite: Exploration of the P1 residue in 3CL protease inhibitors leading to the discovery of a 2-tetrahydrofuran P1 replacement. Bioorg.Med.Chem., 100, 2024
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2023-10-10
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