Structure of aldosterone synthase (CYP11B2) in complex with N-[(1R)-1-[5-(6-chloro-1,1-dimethyl-3-oxo-isoindolin-2-yl)-3-pyridyl]ethyl]methanesulfonamide
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Structure of aldosterone synthase (CYP11B2) in complex with N-[(1R)-1-[5-(6-chloro-1,1-dimethyl-3-oxo-isoindolin-2-yl)-3-pyridyl]ethyl]methanesulfonamide Descriptor: Cytochrome P450 11B2, mitochondrial, HEME C, ... Authors: Kuglstatter, A, Joseph, C, Benz, J. Deposit date: 2020-02-03 Release date: 2020-06-24 Last modified: 2024-05-01 Method: X-RAY DIFFRACTION (3 Å) Cite: Discovery of 3-Pyridyl Isoindolin-1-one Derivatives as Potent, Selective, and Orally Active Aldosterone Synthase (CYP11B2) Inhibitors. J.Med.Chem., 63, 2020
创建时间：
2020-02-03
