Figure 4, Extended Figure 1 - Flow Cytometry Raw Data

Raw Flow Data related to Figure 4. Parasite growth and commitment in presence of an inhibitor of hAgo2. Pf2004 parasites were treated with the Ago2 inhibitor BCI-137 at various concentrations or vehicle (DMSO) and assessed for asexual parasitemia and gametocytemia by flow cytometry. A) Parasite multiplication rate (PMR) over two cycles of asexual replication. B) Gametocyte conversion rate under non-induced and gametocyte-induced conditions. Shown is the mean ± SD of n = 2, with 3 technical replicates each.andExtended Figure 2. Parasite growth and commitment in presence of an inhibitor of hAgo2. Pf2004 parasites were treated with the Ago2 inhibitor BCI-137 at various concentrations or vehicle (DMSO) and assessed for asexual parasitemia and gametocytemia by flow cytometry. (A) Parasite multiplication rate (PMR) over two cycles of asexual replication. (B) Gametocyte conversion rate under non-induced and gametocyte-induced conditions. 1 % DMSO is the vehicle control corresponding to 100 μM BCI-137, 0.1 % DMSO 1000 is the vehicle control corresponding to 10 μM BCI-137. Shown is the mean ± SD of n = 2, with 3 technical replicates each.