首页/数据集/Genome-wide profiling characterizes CRCs with genetic instability and specific routes to HLA class I loss and immunoescape

Genome-wide profiling characterizes CRCs with genetic instability and specific routes to HLA class I loss and immunoescape

ChEBI2011-02-28 更新2026-07-21 收录

免疫逃逸机制

HLA分子丢失分析

数据链接：

https://www.ebi.ac.uk/biostudies/ArrayExpress/studies/E-GEOD-27544 数据链接链接失效反馈

官方服务：

资源简介：

Genome-wide profiling characterizes CRCs with genetic instability and specific routes to HLA class I loss and immunoescape

应用场景：

创建时间：

2011-02-28

病毒抗原进化

免疫逃逸机制

The hypothesis that evolvability - the capacity to evolve by natural selection - is itself the object of natural selection is highly intriguing but remains controversial due in large part to a paucity

NIAID Data Ecosystem100

Gli2 Facilitates Tumor Immune Evasion and Immunotherapeutic Resistance by Coordinating Wnt Ligand and Prostaglandin Synthesis [scRNAseq]

免疫逃逸机制

免疫治疗联合策略

Therapeutic resistance to immune checkpoint blockade remains a prevalent obstacle across many cancer types, and an improved mechanistic understanding of this process could lead to effective combinatio

NIAID Data Ecosystem60

Human Tumour Immune Evasion via TGF-β Blocks NK Cell Activation but Not Survival Allowing Therapeutic Restoration of Anti-Tumour Activity

免疫逃逸机制

细胞功能调控

Immune evasion is now recognized as a key feature of cancer progression. In animal models, the activity of cytotoxic lymphocytes is suppressed in the tumour microenvironment by the immunosuppressive c

Figshare2016-01-18 更新40

HE4 regulates anticancer immune evasion by upregulating PD-L1 expression on macrophages through the IFN-?R-STAT3 axis [L1MKK]

免疫逃逸机制

PD-L1调控

Current immune checkpoint inhibitors (ICIs) targeting PD-L1/PD-1 have achieved great success in clinical cancer treatment. However, it still faces great challenges, such as a low overall response rate

NIAID Data Ecosystem70

Phagolysosomal proteomics identifies DHN-melanin-regulated processes in activated macrophage in response to Aspergillus fumigatus conidia

免疫逃逸机制

吞噬溶酶体蛋白质组学

Infection by the human pathogenic fungus Aspergillus fumigatus is initialized by the outgrowth of asexual spores (conidia) into the lung tissue of the immunocompromised host following an inhalation of

NIAID Data Ecosystem40

Genome-wide profiling characterizes CRCs with genetic instability and specific routes to HLA class I loss and immunoescape

资源简介：

相关数据集