Liquid chromatography–tandem mass spectrometer (LC/MS-MS) of samples from the patients with A3G4 and the search result through NCBInr and Swiss-Prot database performed by Mascot.

*1emPAI (Exponentially Modified Protein Abundance Index) is calculated for the estimation of absolute protein amount as follow; emPAI = 10 Nobserved/Nobservable−1.*2Probability Based Mowse Score. Ions score is −10*Log(P), where P is the probability that the observed match is a random event. Individual ions scores >16 indicate identity or extensive homology (p