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The novel-cell free bioactive formulation (BIOF2) modulates specific osteoarthritis’ detrimental and protective genes: A microarray analysis

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NIAID Data Ecosystem2026-03-12 收录
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https://www.ncbi.nlm.nih.gov/geo/query/acc.cgi?acc=GSE165567
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A novel-cell free bioactive formulation (BIOF2), US Patent No. 9669074B2, for arthrosic chondrocytes has been recently developed and proved as effective for treating severe knee osteoarthritis, we evaluated transcriptome changes in BIOF2-treated synovial fluid cells, isolated from patients with severe knee osteoarthritis to establish BIOF2 mechanism of action. A transcriptomic analysis of a pool of 3 cells samples from the synovial fluid of severe osteoarthritic knees exposed to BIOF2 for 48 hours was carried out compared to samples without treatment.
创建时间:
2021-01-30
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